Many researchers face the problem of missing data in longitudinal research. Especially, high risk samples are characterized by missing data which can complicate analyses and the interpretation of results. In the current study, our aim was to find the most optimal and best method to deal with the missing data in a specific study with many missing data on the outcome variable. Therefore, different techniques to handle missing data were evaluated, and a solution to efficiently handle substantial amounts of missing data was provided. A simulation study was conducted to determine the most optimal method to deal with the missing data. Results revealed that multiple imputation (MI) using predictive mean matching was the most optimal method with respect to lowest bias and the smallest confidence interval (CI) while maintaining power. Listwise deletion and last observation carried backward also scored acceptable with respect to bias; however, CIs were much larger and sample size almost halved using these methods. Longitudinal research in high risk samples could benefit from using MI in future research to handle missing data. The paper ends with a checklist for handling missing data.

Peeters, M., Zondervan-Zwijnenburg, M., Vink, G., & Van de Schoot, R. (2015). How to handle missing data: A comparison of different approaches. European Journal of Developmental Psychology, 12(4), 377-394.

Margot Peeters
Margot studies longitudinal analyzing techniques to study the development of adolescents in the most efficient way. Techniques include latent transition, zero inflated, survival analysis, missing data analysis and Bayesian statistics.
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PhD Student

In her PhD project, Mariëlle focuses on including prior knowledge in statistical analyses (informative Bayesian research) and confronting prior knowledge with new data.