We argue that depending on p-values to reject null hypotheses, including a recent call for changing the canonical alpha level for statistical significance from .05 to .005, is deleterious for the finding of new discoveries and the progress of science. Given that blanket and variable criterion levels both are problematic, it is sensible to dispense with significance testing altogether. There are alternatives that address study design and determining sample sizes much more directly than significance testing does; but none of the statistical tools should replace significance testing as the new magic method giving clear-cut mechanical answers. Inference should not be based on single studies at all, but on cumulative evidence from multiple independent studies. When evaluating the strength of the evidence, we should consider, for example, auxiliary assumptions, the strength of the experimental design, or implications for applications. To boil all this down to a binary decision based on a p-value threshold of .05, .01, .005, or anything else, is not acceptable.

Trafimow D, Amrhein V, Areshenkoff CN, Barrera-Causil C, Beh EJ, Bilgiç Y, Bono R, Bradley MT, Briggs WM, Cepeda-Freyre HA, Chaigneau SE, Ciocca DR, Carlos Correa J, Cousineau D, de Boer MR, Dhar SS, Dolgov I, Gómez-Benito J, Grendar M, Grice J, Guerrero-Gimenez ME, Gutiérrez A, Huedo-Medina TB, Jaffe K, Janyan A, Karimnezhad A, Korner-Nievergelt F, Kosugi K, Lachmair M, Ledesma R, Limongi R, Liuzza MT, Lombardo R, Marks M, Meinlschmidt G, Nalborczyk L, Nguyen HT, Ospina R, Perezgonzalez JD, Pfister R, Rahona JJ, Rodríguez-Medina DA, Romão X, Ruiz-Fernández S, Suarez I, Tegethoff M, Tejo M, van de Schoot R, Vankov I, Velasco-Forero S, Wang T, Yamada Y, Zoppino FC, Marmolejo-Ramos F. (2017Manipulating the alpha level cannot cure significance testing – comments on "Redefine statistical significance" PeerJ Preprints 5:e3411v1  https://doi.org/10.7287/peerj.preprints.3411v1

This is a reply to Benjamin et al. 2017. Redefine statistical significance. Nature Human Behaviour 1, 0189.